OR2A2

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR2A2 mutation is significantly associated with the mutation status of many other genes, with 1,723 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2A2-associated genes across cancer lineages are PDE3A, TEX14, and PPP1R13B. Each is linked with OR2A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2A2-to-partner and partner-to-OR2A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A2→partner) and Y-score (partner→OR2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPDE3A →+4.000+5.050.008.00814
BLOOD_LymphomaTEX14 →+4.584+4.584.007.00714
BLOOD_LeukemiaPPP1R13B →+4.321+5.285.005.00514
BLOOD_LeukemiaTTF2 →+4.321+5.285.005.00514
LARGE_INTESTINERIMS1 →+1.366+2.630.008.00814
BLOOD_LeukemiaMAGEL2 →+4.321+5.285.005.00513
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,723 associations by consensus.

Exploration