Across TCGA cell cohorts, OR2A14 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2A14-associated genes across cancer lineages are SERPINA12, OPRPN, and USP17L3. Each is linked with OR2A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A14-to-partner and partner-to-OR2A14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A14→partner) and Y-score (partner→OR2A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	SERPINA12 →	+0.016	+5.614	<.001	.002	3	1
PANCREAS	OPRPN →	+0.029	+5.000	<.001	.006	3	1
PANCREAS	USP17L3 →	+0.016	+5.000	<.001	.006	3	1
CNS	KRTAP11-1 →	+0.017	+4.754	<.001	.005	3	1
CNS	MBD3L4 →	+0.014	+4.321	<.001	.009	3	1
LARGE_INTESTINE	SH3GL2 →	+1.381	+3.252	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

OR2A14 survival (RNA) · tumor vs normal (RNA) · all OR2A14 data types