Across TCGA cell cohorts, OR2A12 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR2A12-associated genes across cancer lineages are MC2R, KRTAP12-3, and FCER2. Each is linked with OR2A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A12-to-partner and partner-to-OR2A12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A12→partner) and Y-score (partner→OR2A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MC2R →	+0.004	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.053	+4.539	<.001	.007	3	1
CNS	FCER2 →	+0.085	+3.758	.003	.004	3	1
CNS	KRT37 →	+0.021	+3.000	<.001	.006	3	1
CNS	BPIFA2 →	+0.166	+3.145	.004	.004	3	1
CNS	ENPP6 →	+1.035	+2.959	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

OR2A12 survival (RNA) · tumor vs normal (RNA) · all OR2A12 data types