OR1N2

Across TCGA cell cohorts, OR1N2 mutation is significantly associated with the mutation status of many other genes, with 379 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR1N2-associated genes across cancer lineages are SEL1L3, KCNJ12, and HP1BP3. Each is linked with OR1N2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR1N2-to-partner and partner-to-OR1N2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEL1L3 grouped by OR1N2-low versus OR1N2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1N2→partner) and Y-score (partner→OR1N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SEL1L3 →	+5.772	+5.772	.002	.002	1	3
SKIN	KCNJ12 →	+5.392	+4.824	.004	.004	1	3
LUNG_NSCLC_LUAD	HP1BP3 →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	BCLAF3 →	+4.772	+5.339	.004	.004	1	2
SKIN	GDF7 →	+4.392	+4.392	.009	.009	1	2
SKIN	CDH8 →	+2.655	+4.113	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 379 associations by consensus.

SEL1L3 by OR1N2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →