OR1N2

Across TCGA pan-cancer cohorts, OR1N2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated OR1N2 data layer compared with 5 for mutation status.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher OR1N2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR1N2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

TGCT, ESCA, and READ are the cancer types where OR1N2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	54	view →
ESCA	OS	Median	III,IV	0.590	0.324	.006	39	view →
READ	DFS	Tertile	III,IV	0.438	0.773	.018	24	view →
PAAD	DFS	Tertile	All	0.460	0.304	.023	21	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	18	view →
KIRC	DFS	Tertile	IV	0.374	0.680	.025	18	view →
PRAD	DFS	Tertile	All	0.974	0.727	.001	18	view →
UCEC	DFS	Tertile	All	0.853	0.908	.023	12	view →
SCLC	DFS	Tertile	All	0.427	0.897	.002	10	view →
STAD	DFS	Median	IV	0.643	0.218	.027	9	view →
LIHC	DFS	Tertile	III,IV	0.081	0.413	.048	9	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

OR1N2–TGCT (OS)

Open the TGCT breakdown →