OR1J1

Across TCGA cell cohorts, OR1J1 mutation is significantly associated with the mutation status of many other genes, with 791 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR1J1-associated genes across cancer lineages are REV3L, UNC45B, and NBEAL1. Each is linked with OR1J1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR1J1-to-partner and partner-to-OR1J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REV3L grouped by OR1J1-low versus OR1J1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1J1→partner) and Y-score (partner→OR1J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	REV3L →	+4.187	+5.000	.008	.008	1	3
SOFT_TISSUE	UNC45B →	+5.066	+4.502	.007	.007	1	3
SOFT_TISSUE	NBEAL1 →	+5.651	+5.651	<.001	<.001	1	3
LUNG_NSCLC_LUAD	WDR24 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	AGAP3 →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	VPS11 →	+4.187	+5.000	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 791 associations by consensus.

REV3L by OR1J1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →