OR1I1

Across TCGA patient cohorts, OR1I1 protein abundance is significantly associated with the RNA expression of many other genes, with 221 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible OR1I1-associated genes across cancer lineages are PPP6R2, REC8, and ARFRP1. Each is linked with OR1I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1I1-to-partner and partner-to-OR1I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OR1I1 versus PPP6R2 in HNSC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1I1→partner) and Y-score (partner→OR1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPP6R2 →	+0.712	+0.406	.006	<.001	3	1
HNSC	REC8 →	+0.801	+0.308	.002	.003	3	1
HNSC	ARFRP1 →	+0.797	+0.296	.006	.006	3	1
HNSC	ACTR5 →	+1.048	+0.288	.006	.008	3	1
HNSC	ACOD1 →	+0.720	+0.286	.003	.008	3	1
HNSC	TNFRSF10A →	+1.701	+0.296	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 221 associations by consensus.

OR1I1 vs PPP6R2 — HNSC

Explore this scatter interactively →