OR1I1

Across TCGA pan-cancer cohorts, OR1I1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR1I1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OR1I1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR1I1 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD and THCA are the cancer types where OR1I1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR1I1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.021	.016	3	view →
THCA	Female	All	+0.005	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR1I1–COAD

Open the COAD breakdown →