OR1I1

Across TCGA patient cohorts, OR1I1 protein abundance is significantly associated with the protein abundance of many other proteins, with 184 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible OR1I1-associated proteins across cancer lineages are NUCKS1_S79, CAMSAP1_S1427, and SHTN1_S494. Each is linked with OR1I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1I1-to-partner and partner-to-OR1I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OR1I1 versus NUCKS1_S79 in HNSC, with a Pearson correlation of -0.90.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1I1→partner) and Y-score (partner→OR1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUCKS1_S79 →	-1.423	-0.459	.003	<.001	3	1
HNSC	CAMSAP1_S1427 →	-1.026	-0.348	<.001	<.001	3	1
HNSC	SHTN1_S494 →	+0.788	+0.489	.001	<.001	3	1
HNSC	VCL_S566 →	-1.307	-0.537	.001	<.001	3	1
HNSC	H1-10_S113 →	+1.651	+0.348	<.001	<.001	2	1
HNSC	AMZ2 →	-0.632	-0.336	.009	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

OR1I1 vs NUCKS1_S79 — HNSC

Explore this scatter interactively →