OR1I1

Across TCGA cell cohorts, OR1I1 RNA expression is significantly associated with the mutation status of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR1I1-associated genes across cancer lineages are GNB1, EPHA6, and KIDINS220. Each is linked with OR1I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1I1-to-partner and partner-to-OR1I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNB1 grouped by OR1I1-low versus OR1I1-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1I1→partner) and Y-score (partner→OR1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GNB1 →	+4.662	+0.010	.003	<.001	3	1
BLOOD_Lymphoma	EPHA6 →	+4.247	+0.008	.004	<.001	3	1
LUNG_NSCLC_LUAD	KIDINS220 →	+4.266	+0.010	.004	<.001	3	1
LUNG_NSCLC_LUAD	RAVER1 →	+4.681	+0.012	.003	<.001	3	1
LUNG_NSCLC_LUAD	RPRD2 →	+4.681	+0.012	.003	<.001	3	1
LUNG_NSCLC_LUAD	RASEF →	+6.266	+0.020	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

GNB1 by OR1I1 expression — BLOOD_Lymphoma

Explore this box plot interactively →