OR1D4

Across TCGA patient cohorts, OR1D4 mutation is significantly associated with the RNA expression of many other genes, with 237 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR1D4-associated genes across cancer lineages are RPL23AP45, RN7SKP228, and MIR141. Each is linked with OR1D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1D4-to-partner and partner-to-OR1D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP45 grouped by OR1D4-low versus OR1D4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1D4→partner) and Y-score (partner→OR1D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP45 →	+0.037	+2.638	<.001	.006	3	2
SKCM	RN7SKP228 →	+0.071	+2.970	<.001	.008	3	2
UCEC	MIR141 →	+0.724	+2.620	<.001	.008	3	2
UCEC	HLA-DPA2 →	+0.130	+4.324	.002	<.001	3	2
UCEC	IMPDH1P4 →	+0.253	+2.872	<.001	.006	3	2
LUSC	AFF2-IT1 →	+0.264	+4.110	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

RPL23AP45 by OR1D4 expression — SKCM

Explore this box plot interactively →