OR14K1

Across TCGA cell cohorts, OR14K1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible OR14K1-associated genes across cancer lineages are OR1G1, OR52L1, and OR56A4. Each is linked with OR14K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14K1-to-partner and partner-to-OR14K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1G1 grouped by OR14K1-low versus OR14K1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14K1→partner) and Y-score (partner→OR14K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR1G1 →	+0.057	+4.392	<.001	.003	3	1
OESOPHAGUS	OR52L1 →	+0.181	+4.017	<.001	.007	3	1
OESOPHAGUS	OR56A4 →	+0.407	+4.017	<.001	.007	3	1
OESOPHAGUS	OR6C76 →	+0.065	+4.857	<.001	<.001	3	1
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
LUNG_SCLC	RNASE3 →	+0.068	+4.817	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR1G1 by OR14K1 expression — OESOPHAGUS

Explore this box plot interactively →