OR14K1

Across TCGA pan-cancer cohorts, OR14K1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR14K1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR14K1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR14K1 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

BRCA, THCA, and PRAD are the cancer types where OR14K1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR14K1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	+0.179	.010	6	view →
THCA	All	All	−0.041	.003	4	view →
PRAD	All	All	+0.160	.002	2	view →
COAD	All	II,III,IV	−0.035	.015	2	view →
KICH	All	All	−0.028	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR14K1–BRCA

Open the BRCA breakdown →