OR13C5

Across TCGA patient cohorts, OR13C5 mutation is significantly associated with the RNA expression of many other genes, with 541 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13C5-associated genes across cancer lineages are TM2D3, MFSD14C, and RNU6-218P. Each is linked with OR13C5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C5-to-partner and partner-to-OR13C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TM2D3 grouped by OR13C5-low versus OR13C5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C5→partner) and Y-score (partner→OR13C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TM2D3 →	+0.447	+3.362	.004	.005	3	2
UCEC	MFSD14C →	+0.856	+3.354	<.001	.005	3	2
UCEC	RNU6-218P →	+0.441	+2.219	.008	.005	3	2
LUSC	P3R3URF →	+0.101	+4.578	<.001	.005	3	2
SKCM	TEX30 →	+0.578	+1.809	.001	.001	3	2
LUAD	IGLVI-42 →	+0.064	+4.122	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 541 associations by consensus.

TM2D3 by OR13C5 expression — UCEC

Explore this box plot interactively →