IGLVI-42

Q-omics provides the consensus-scored IGLVI-42 profile across patient tissues and cancer cell-line models. IGLVI-42 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in THCA. Additionally, IGLVI-42 RNA expression shows 3,784 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight THCA, and STAD as cancer lineages where IGLVI-42 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes IGLVI-42 survival associations across molecular data types. IGLVI-42 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGLVI-42 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	THCA (54)	view →

This table ranks reproducible IGLVI-42 RNA expression–survival associations across cancer types. High IGLVI-42 expression shows unfavorable associations in THCA, LUAD, PCPG, HNSC, DLBC and LUSC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for IGLVI-42 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.240	0.931	<.001	54	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	36	view →
PCPG	DFS	Tertile	All	0.074	0.867	<.001	36	view →
HNSC	DFS	Tertile	III,IV	0.179	0.615	.005	36	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	28	view →
LUSC	DFS	Tertile	II,III,IV	0.139	0.663	.027	27	view →

Pink = unfavorable, green = favorable. all 9 lineages →

IGLVI-42-THCA (OS)

Explore this curve interactively →