OR13C4

Across TCGA patient cohorts, OR13C4 mutation is significantly associated with the RNA expression of many other genes, with 1,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13C4-associated genes across cancer lineages are DEFB127, FAM74A6, and OR5BB1P. Each is linked with OR13C4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C4-to-partner and partner-to-OR13C4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB127 grouped by OR13C4-low versus OR13C4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C4→partner) and Y-score (partner→OR13C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DEFB127 →	+0.071	+4.505	.001	.009	3	2
BRCA	FAM74A6 →	+0.023	+5.324	<.001	.003	3	2
READ	OR5BB1P →	+0.055	+6.257	<.001	.001	3	2
HNSC	MRPS11P1 →	+0.066	+4.578	<.001	.008	3	2
STAD	SCARNA18B →	+0.378	+3.203	.006	.009	3	2
HNSC	RN7SL317P →	+0.196	+4.245	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,318 associations by consensus.

DEFB127 by OR13C4 expression — HNSC

Explore this box plot interactively →