OR13C4

Across TCGA pan-cancer cohorts, OR13C4 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated OR13C4 data layer compared with 8 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher OR13C4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR13C4 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

THCA, KIRC, and UCEC are the cancer types where OR13C4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	III,IV	0.500	0.876	<.001	36	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
UCEC	DFS	Tertile	All	0.763	0.901	.010	36	view →
SCLC	OS	Tertile	All	0.055	0.653	<.001	27	view →
HNSC	DFS	Tertile	II,III,IV	0.211	0.597	.028	27	view →
MESO	DFS	Tertile	III,IV	0.078	0.376	.012	27	view →
STAD	DFS	Tertile	III,IV	0.284	0.592	.014	18	view →
BLCA	DFS	Tertile	IV	0.122	0.471	.006	18	view →
BRCA	DFS	Tertile	All	0.368	0.530	.012	18	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →
LUAD	DFS	Tertile	All	1.000	0.336	.030	12	view →
PCPG	DFS	Tertile	All	0.063	0.921	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

OR13C4–THCA (DFS)

Open the THCA breakdown →