olfactory receptor family 11 subfamily L member 1Genealiases: []
Q-omics provides the consensus-scored OR11L1 profile across patient tissues and cancer cell-line models. OR11L1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, OR11L1 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, OR11L1 RNA expression shows 6,742 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ACC, THCA, and STAD as cancer lineages where OR11L1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR11L1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR11L1 survival associations across molecular data types. OR11L1 RNA expression shows survival associations in the most cancer types (12), followed by mutation status (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR11L1 RNA expression–survival associations across cancer types. High OR11L1 expression shows unfavorable associations in ACC, SCLC, LIHC, BLCA, PAAD and LGG. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for OR11L1 RNA expression.
This table summarizes OR11L1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for OR11L1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR11L1 shows lower tumor expression in THCA. The THCA box plot shows higher OR11L1 RNA expression in normal versus tumor tissue (log2 FC = −0.178, t-test p < 0.001).
This table shows molecular features associated with OR11L1 in patient tissues and cancer cell lines. In patient samples, OR11L1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR11L1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in OVARY and SOFT_TISSUE.
