Across TCGA cell cohorts, OR11L1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR11L1-associated genes across cancer lineages are CCDC63, BSX, and PIN4. Each is linked with OR11L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11L1-to-partner and partner-to-OR11L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11L1→partner) and Y-score (partner→OR11L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CCDC63 →	+0.032	+4.584	.002	.001	3	1
LUNG_NSCLC_LUSC	BSX →	+0.048	+4.108	<.001	.005	3	1
LUNG_NSCLC_LUAD	PIN4 →	+0.653	+3.206	.006	.006	3	1
LUNG_NSCLC_LUAD	CROCC2 →	+0.172	+2.688	<.001	.002	3	1
LUNG_SCLC	SPATA48 →	+0.013	+2.847	.001	.009	3	1
LUNG_SCLC	CD3D →	+0.448	+2.754	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

OR11L1 survival (RNA) · tumor vs normal (RNA) · all OR11L1 data types