OR10S1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10S1 mutation is significantly associated with the RNA expression of many other genes, with 1,674 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10S1-associated genes across cancer lineages are SKA1, NCAPH2, and KCNK15. Each is linked with OR10S1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10S1-to-partner and partner-to-OR10S1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10S1→partner) and Y-score (partner→OR10S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSKA1 →+0.659+3.609.004.00133
UCECNCAPH2 →+0.706+3.716<.001<.00133
UCECKCNK15 →-1.755-3.689<.001.00133
SKCMMIR6882 →+0.127+2.247<.001.00433
LUSCASS1 →-0.977-2.754<.001.00333
SKCMMAP6 →-0.436-3.173.004<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,674 associations by consensus.

Exploration