OR10G8

Across TCGA pan-cancer cohorts, OR10G8 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OR10G8 data layer compared with 7 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher OR10G8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR10G8 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

THYM, LIHC, and SARC are the cancer types where OR10G8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LIHC	DFS	Median	II,III,IV	0.044	0.414	<.001	9	view →
SARC	OS	Median	All	0.156	0.767	.001	6	view →
PRAD	OS	Median	All	0.369	0.887	<.001	6	view →
LUAD	OS	Median	III,IV	1.000	0.267	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OR10G8–THYM (OS)

Open the THYM breakdown →