OR10G8

Across TCGA pan-cancer cohorts, OR10G8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR10G8’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OR10G8 RNA is repressed in tumor relative to normal tissue. In most cancer types OR10G8 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

COAD and BRCA are the cancer types where OR10G8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR10G8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.009	.043	2	view →
BRCA	All	All	−0.005	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR10G8–COAD

Open the COAD breakdown →