OR10G8

Across TCGA patient cohorts, OR10G8 mutation is significantly associated with the RNA expression of many other genes, with 1,876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10G8-associated genes across cancer lineages are LINC02403, ZNF530, and NUP160. Each is linked with OR10G8 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR10G8-to-partner and partner-to-OR10G8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02403 grouped by OR10G8-low versus OR10G8-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G8→partner) and Y-score (partner→OR10G8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC02403 →	+0.215	+2.735	<.001	.004	3	3
UCEC	ZNF530 →	+0.433	+2.098	.001	.003	3	3
UCEC	NUP160 →	+0.549	+3.624	.002	.001	3	3
UCEC	TNNC2 →	-0.929	-4.000	.001	<.001	3	2
UCEC	CACTIN →	+0.391	+2.595	<.001	<.001	3	2
UCEC	LIG1 →	+0.471	+2.831	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,876 associations by consensus.

LINC02403 by OR10G8 expression — HNSC

Explore this box plot interactively →