OR10G8

Across TCGA cell cohorts, OR10G8 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR10G8-associated genes across cancer lineages are OR11A1, KRTAP9-4, and OR5V1. Each is linked with OR10G8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10G8-to-partner and partner-to-OR10G8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11A1 grouped by OR10G8-low versus OR10G8-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10G8→partner) and Y-score (partner→OR10G8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR11A1 →	+0.016	+5.285	<.001	.003	3	1
STOMACH	KRTAP9-4 →	+0.040	+5.285	<.001	.003	3	1
STOMACH	OR5V1 →	+0.056	+5.285	<.001	.003	3	1
STOMACH	OR12D1 →	+0.153	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.071	+4.813	<.001	<.001	3	1
LUNG_NSCLC_LUAD	LIPN →	+0.027	+3.947	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR11A1 by OR10G8 expression — STOMACH

Explore this box plot interactively →