OPN1LW

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OPN1LW RNA expression is significantly associated with the go_rna of many other GO terms, with 6,229 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OPN1LW-associated GO terms across cancer lineages are Myeloid leukocyte differentiation, Intrinsic apoptotic signaling pathway in response to DNA damage, and Positive regulation of apoptotic signaling pathway. Each is linked with OPN1LW in more than 8 cancer types. Because this analysis shows association rather than direction, both OPN1LW-to-partner and partner-to-OPN1LW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid leukocyte differentiation grouped by OPN1LW-low versus OPN1LW-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1LW→partner) and Y-score (partner→OPN1LW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADMyeloid leukocyte differentiation →+0.078+0.049<.001<.00139
STADIntrinsic apoptotic signaling pathway in response to DNA damage →+0.091+0.049<.001<.00139
STADPositive regulation of apoptotic signaling pathway →+0.083+0.041<.001<.00139
STADDetoxification →+0.055+0.040<.001<.00138
STADRegulation of mitochondrion organization →+0.078+0.040<.001<.00138
STADPeptidyl-tyrosine modification →+0.065+0.049<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,229 associations by consensus.

Myeloid leukocyte differentiation by OPN1LW expression — STAD

Box plot of Myeloid leukocyte differentiation in OPN1LW-low vs OPN1LW-high samples in STAD.

Explore this box plot interactively →

Exploration