OPN1LW

Across TCGA cell cohorts, OPN1LW RNA expression is significantly associated with the mutation status of many other genes, with 73 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible OPN1LW-associated genes across cancer lineages are GCN1, EFR3B, and KLHL4. Each is linked with OPN1LW in more than 1 cancer types. Because this analysis shows association rather than direction, both OPN1LW-to-partner and partner-to-OPN1LW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCN1 grouped by OPN1LW-low versus OPN1LW-high in BLOOD_Myeloma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1LW→partner) and Y-score (partner→OPN1LW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	GCN1 →	+3.285	+0.012	.009	.002	3	1
BLOOD_Lymphoma	EFR3B →	+5.209	+0.039	.005	<.001	3	1
LUNG_NSCLC_LUSC	KLHL4 →	+4.643	+0.020	.008	<.001	3	1
LUNG_NSCLC_LUSC	XYLT1 →	+4.643	+0.020	.008	<.001	3	1
LUNG_SCLC	VPS9D1 →	+5.029	+0.242	.006	<.001	3	1
BLOOD_Myeloma	CNTRL →	+4.285	+0.022	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

GCN1 by OPN1LW expression — BLOOD_Myeloma

Explore this box plot interactively →