OPN1LW

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OPN1LW mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OPN1LW-associated genes across cancer lineages are CEACAM3 and LILRA5. Each is linked with OPN1LW in more than 1 cancer types. Because this analysis shows association rather than direction, both OPN1LW-to-partner and partner-to-OPN1LW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEACAM3 grouped by OPN1LW-low versus OPN1LW-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPN1LW→partner) and Y-score (partner→OPN1LW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSCEACAM3 →+0.045+4.321<.001.00931
CNSLILRA5 →+0.087+5.357<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CEACAM3 by OPN1LW expression — CNS

Box plot of CEACAM3 in OPN1LW-low vs OPN1LW-high samples in CNS.

Explore this box plot interactively →

Exploration