OPCML-IT1

Across TCGA patient cohorts, OPCML-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,314 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPCML-IT1-associated proteins across cancer lineages are SPTAN1, SPTBN1, and ADD1. Each is linked with OPCML-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OPCML-IT1-to-partner and partner-to-OPCML-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPCML-IT1 versus SPTAN1 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPCML-IT1→partner) and Y-score (partner→OPCML-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPTAN1 →	+0.423	+0.927	<.001	<.001	3	3
GBM	SPTBN1 →	+0.394	+0.736	<.001	.002	3	3
GBM	ADD1 →	+0.416	+1.211	<.001	<.001	3	3
PDAC	SPTAN1_S1217 →	+0.381	+0.020	<.001	.006	3	2
PDAC	TCEAL3 →	+0.304	+0.022	.005	.002	3	2
GBM	TRIM2 →	+0.427	+0.866	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,314 associations by consensus.

OPCML-IT1 vs SPTAN1 — GBM

Explore this scatter interactively →