OLIG3

Across TCGA patient cohorts, OLIG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,940 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible OLIG3-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Epithelial cell proliferation involved in lung morphogenesis, and Positive regulation of telomerase activity. Each is linked with OLIG3 in more than 9 cancer types. Because this analysis shows association rather than direction, both OLIG3-to-partner and partner-to-OLIG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by OLIG3-low versus OLIG3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OLIG3→partner) and Y-score (partner→OLIG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein ubiquitination →	+0.057	+0.142	<.001	<.001	3	10
TGCT	Epithelial cell proliferation involved in lung morphogenesis →	+0.075	+0.485	<.001	<.001	3	9
STAD	Positive regulation of telomerase activity →	+0.050	+0.096	<.001	.001	3	8
TGCT	Nephron morphogenesis →	+0.060	+0.709	<.001	<.001	3	8
STAD	Mitochondrial gene expression →	+0.061	+0.110	<.001	.007	2	9
GBM	Positive regulation of mitotic cell cycle →	+0.023	+0.319	<.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,940 associations by consensus.

Regulation of protein ubiquitination by OLIG3 expression — STAD

Explore this box plot interactively →