OLIG3

Across TCGA pan-cancer cohorts, OLIG3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OLIG3’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where OLIG3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OLIG3 is over-expressed in tumor.

UCEC, PRAD, and KIRP are the cancer types where OLIG3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OLIG3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.386	.001	4	view →
PRAD	All	All	+0.229	.003	2	view →
KIRP	All	All	+0.185	.017	1	view →
LUAD	All	All	+0.074	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

OLIG3–UCEC

Open the UCEC breakdown →