OLIG3

Across TCGA cell cohorts, OLIG3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OLIG3-associated genes across cancer lineages are OR11A1, KRTAP10-7, and ACER1. Each is linked with OLIG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLIG3-to-partner and partner-to-OLIG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11A1 grouped by OLIG3-low versus OLIG3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLIG3→partner) and Y-score (partner→OLIG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR11A1 →	+0.006	+5.196	<.001	.005	3	1
STOMACH	KRTAP10-7 →	+0.026	+5.285	<.001	.003	3	1
LARGE_INTESTINE	ACER1 →	+0.111	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR11A1 by OLIG3 expression — OVARY

Explore this box plot interactively →