OGFOD3

Across TCGA patient cohorts, OGFOD3 mutation is significantly associated with the RNA expression of many other genes, with 955 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OGFOD3-associated genes across cancer lineages are RNU6-1084P, MIR598, and C12orf43. Each is linked with OGFOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD3-to-partner and partner-to-OGFOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1084P grouped by OGFOD3-low versus OGFOD3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD3→partner) and Y-score (partner→OGFOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1084P →	+0.221	+4.912	<.001	.005	3	2
HNSC	MIR598 →	+0.363	+4.270	.004	.008	3	2
UCEC	C12orf43 →	+0.269	+2.617	.008	.005	3	2
UCEC	UTP15 →	+0.433	+2.815	.002	.001	3	2
SKCM	NUDT2 →	+0.656	+3.328	<.001	.005	3	2
UCEC	CENPN →	+0.786	+3.828	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 955 associations by consensus.

RNU6-1084P by OGFOD3 expression — HNSC

Explore this box plot interactively →