OGFOD3

Across TCGA patient cohorts, OGFOD3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OGFOD3-associated genes across cancer lineages are HSP70, Tuberin, and ATM. Each is linked with OGFOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD3-to-partner and partner-to-OGFOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSP70 grouped by OGFOD3-low versus OGFOD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD3→partner) and Y-score (partner→OGFOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSP70 →	-0.373	-2.990	.028	.036	3	2
UCEC	Tuberin →	+0.374	+2.321	.001	.033	3	2
UCEC	ATM →	-0.530	-1.700	.005	.044	3	2
UCEC	FoxM1 →	+0.290	+1.700	.008	.044	3	1
UCEC	FOXO3a_pS318_S321 →	-0.108	-2.321	.042	.033	3	1
UCEC	GATA6 →	-0.130	-2.215	.047	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

HSP70 by OGFOD3 expression — UCEC

Explore this box plot interactively →