ODF3

Across TCGA patient cohorts, ODF3 mutation is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODF3-associated genes across cancer lineages are TXNL4AP1, OFD1P1Y, and RPL23P11. Each is linked with ODF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF3-to-partner and partner-to-ODF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXNL4AP1 grouped by ODF3-low versus ODF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3→partner) and Y-score (partner→ODF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TXNL4AP1 →	+0.260	+3.951	<.001	.005	3	2
LIHC	OFD1P1Y →	+0.063	+4.308	.007	.007	3	2
LIHC	RPL23P11 →	+0.162	+5.547	<.001	<.001	3	2
SKCM	DPP3P1 →	+0.016	+3.913	.006	.006	3	2
LUSC	RBMX2P4 →	+0.151	+6.918	<.001	<.001	3	2
LUSC	VN1R91P →	+0.306	+6.894	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

TXNL4AP1 by ODF3 expression — COAD

Explore this box plot interactively →