ODF3

Across TCGA pan-cancer cohorts, ODF3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ODF3 data layer compared with 4 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ODF3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ODF3 expression acts as an unfavorable survival marker, although some lineages such as UCS and TGCT show a favorable association.

UCS, LIHC, and HNSC are the cancer types where ODF3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	III,IV	0.721	0.262	.004	60	view →
LIHC	OS	Tertile	II,III,IV	0.478	0.739	.002	60	view →
HNSC	DFS	Tertile	All	0.182	0.391	.004	60	view →
KICH	OS	Quartile	III,IV	0.205	0.913	.008	39	view →
LUSC	DFS	Quartile	All	0.675	0.788	.023	16	view →
TGCT	DFS	Median	All	0.884	0.734	.023	16	view →
SKCM	OS	Quartile	III,IV	0.857	0.640	.025	12	view →
PRAD	DFS	Tertile	All	0.820	0.907	.005	12	view →
PCPG	DFS	Quartile	All	0.518	0.893	.010	11	view →
ACC	OS	Median	III,IV	0.808	0.421	.012	8	view →
PAAD	DFS	Quartile	All	0.229	0.398	.034	8	view →
THYM	DFS	Median	All	0.905	0.647	.020	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ODF3–UCS (DFS)

Open the UCS breakdown →