ODF2L

Across TCGA cell cohorts, ODF2L mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ODF2L-associated genes across cancer lineages are INSRR, SPACA1, and OR4D9. Each is linked with ODF2L in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF2L-to-partner and partner-to-ODF2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSRR grouped by ODF2L-low versus ODF2L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF2L→partner) and Y-score (partner→ODF2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	INSRR →	+0.035	+4.557	<.001	.001	3	2
LUNG_NSCLC_LUAD	SPACA1 →	+0.012	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR4D9 →	+0.010	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	FABP9 →	+0.027	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	CT47A6 →	+0.013	+4.078	<.001	.009	3	1
BLOOD_Lymphoma	TLR8 →	+0.252	+4.087	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

INSRR by ODF2L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →