ODF2L

Across TCGA pan-cancer cohorts, ODF2L RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ODF2L data layer compared with 3 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ODF2L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ODF2L expression acts as an unfavorable survival marker, although some lineages such as BLCA and COAD show a favorable association.

KIRC, LGG, and ACC are the cancer types where ODF2L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	IV	0.221	0.445	.002	64	view →
LGG	DFS	Median	All	0.627	0.845	<.001	54	view →
ACC	DFS	Median	All	0.561	0.903	<.001	43	view →
SARC	OS	Quartile	All	0.349	0.592	<.001	35	view →
BLCA	DFS	Quartile	III,IV	0.473	0.180	.003	34	view →
KICH	DFS	Quartile	II,III,IV	0.405	0.937	.002	32	view →
LUSC	DFS	Quartile	All	0.683	0.792	.011	23	view →
COAD	DFS	Tertile	II,III,IV	0.796	0.441	.006	23	view →
THYM	OS	Tertile	All	1.000	0.689	.003	21	view →
LIHC	OS	Median	III,IV	0.869	0.560	.002	20	view →
SKCM	DFS	Median	II,III,IV	0.295	0.155	.004	20	view →
READ	DFS	Tertile	IV	0.328	0.760	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ODF2L–KIRC (DFS)

Open the KIRC breakdown →