OAS1

Across TCGA cell cohorts, OAS1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,654 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OAS1-associated genes across cancer lineages are OAS3, PARP9, and OAS2. Each is linked with OAS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both OAS1-to-partner and partner-to-OAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OAS1 versus OAS3 in BLOOD_Myeloma, with a Pearson correlation of 0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OAS1→partner) and Y-score (partner→OAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OAS3 →	+2.318	+2.560	.003	.003	3	19
UPPER_AERODIGESTIVE_TRACT	PARP9 →	+1.680	+2.884	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	OAS2 →	+2.884	+2.877	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	IFIT3 →	+2.977	+2.884	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	IFI44 →	+3.214	+2.629	<.001	<.001	3	14
OESOPHAGUS	LGALS9 →	+3.108	+3.392	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,654 associations by consensus.

OAS1 vs OAS3 — BLOOD_Myeloma

Explore this scatter interactively →