Across TCGA patient cohorts, NWD1 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NWD1-associated genes across cancer lineages are Caspase-7-cleavedD198, CD20, and NF2. Each is linked with NWD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NWD1-to-partner and partner-to-NWD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NWD1→partner) and Y-score (partner→NWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.974	+2.476	<.001	.009	3	4
COAD	CD20 →	+0.112	+1.703	.011	.013	3	3
UCEC	NF2 →	+0.202	+1.662	.001	.010	3	3
BLCA	Smad4 →	+0.137	+3.000	.043	.036	3	2
COAD	Fibronectin →	+0.444	+2.459	.012	.018	3	2
COAD	mTOR_pS2448 →	-0.150	-2.304	.015	.032	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

NWD1 survival (RNA) · tumor vs normal (RNA) · all NWD1 data types