Across TCGA cell cohorts, NWD1 mutation is significantly associated with the RNA expression of many other genes, with 1,399 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NWD1-associated genes across cancer lineages are G6PC2, OR2AJ1, and FKBP6. Each is linked with NWD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NWD1-to-partner and partner-to-NWD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NWD1→partner) and Y-score (partner→NWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	G6PC2 →	+0.020	+3.115	<.001	.005	3	2
BLOOD_Myeloma	OR2AJ1 →	+0.013	+4.807	<.001	.006	3	2
BLOOD_Leukemia	FKBP6 →	+0.112	+3.034	<.001	.004	3	2
BLOOD_Lymphoma	DPRX →	+0.031	+4.452	<.001	.001	3	2
LUNG_SCLC	URAD →	+0.034	+3.614	<.001	.001	3	2
LARGE_INTESTINE	JOSD1 →	+0.528	+2.043	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,399 associations by consensus.

Exploration

NWD1 survival (RNA) · tumor vs normal (RNA) · all NWD1 data types