NUP205

Across TCGA patient cohorts, NUP205 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,904 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP205-associated proteins across cancer lineages are TNPO3, RRM2, and SMC2. Each is linked with NUP205 in more than 7 cancer types. Because this analysis shows association rather than direction, both NUP205-to-partner and partner-to-NUP205 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP205 versus TNPO3 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP205→partner) and Y-score (partner→NUP205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TNPO3 →	+0.403	+0.589	<.001	.001	3	8
LSCC	RRM2 →	+0.756	+0.758	<.001	<.001	3	8
UCEC	SMC2 →	+0.614	+0.604	<.001	.001	3	8
LSCC	SMC4 →	+0.539	+0.723	<.001	<.001	3	8
LSCC	VRK1 →	+0.758	+0.794	<.001	<.001	3	7
LSCC	ATAD2 →	+0.480	+0.619	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,904 associations by consensus.

NUP205 vs TNPO3 — BRCA

Explore this scatter interactively →