NUP205

Across TCGA patient cohorts, NUP205 protein abundance is significantly associated with the RNA expression of many other genes, with 18,709 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP205-associated genes across cancer lineages are TOP2A, NCAPG2, and ACTR3B. Each is linked with NUP205 in more than 7 cancer types. Because this analysis shows association rather than direction, both NUP205-to-partner and partner-to-NUP205 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP205 versus TOP2A in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP205→partner) and Y-score (partner→NUP205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOP2A →	+1.179	+0.240	<.001	<.001	3	8
LSCC	NCAPG2 →	+0.859	+0.203	<.001	<.001	3	8
OV	ACTR3B →	+0.829	+0.243	<.001	<.001	3	7
HNSC	ABCA8 →	-0.968	-0.149	.001	.002	3	7
OV	FLI1 →	-0.798	-0.263	.001	<.001	3	7
CCRCC	EMCN →	-1.160	-0.165	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,709 associations by consensus.

NUP205 vs TOP2A — LSCC

Explore this scatter interactively →