NUDT7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NUDT7 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NUDT7-associated genes across cancer lineages are OR2AK2 and DCAF4L2. Each is linked with NUDT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT7-to-partner and partner-to-NUDT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AK2 grouped by NUDT7-low versus NUDT7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT7→partner) and Y-score (partner→NUDT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYOR2AK2 →+0.060+4.029<.001.00931
OVARYDCAF4L2 →+0.605+4.321<.001.00411
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2AK2 by NUDT7 expression — OVARY

Box plot of OR2AK2 in NUDT7-low vs NUDT7-high samples in OVARY.

Explore this box plot interactively →

Exploration