NUDT16L1

Across TCGA patient cohorts, NUDT16L1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,648 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT16L1-associated genes across cancer lineages are TMEM186, CIAO3, and MDFIC. Each is linked with NUDT16L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUDT16L1-to-partner and partner-to-NUDT16L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT16L1 versus TMEM186 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT16L1→partner) and Y-score (partner→NUDT16L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TMEM186 →	+0.543	+0.370	<.001	<.001	3	6
BRCA	CIAO3 →	+0.583	+0.327	<.001	<.001	3	5
OV	MDFIC →	-1.092	-0.393	.001	.008	3	5
BRCA	ZSCAN32 →	+0.368	+0.226	<.001	<.001	3	5
BRCA	SIRT3 →	+0.475	+0.358	<.001	<.001	3	5
BRCA	COQ7 →	+0.517	+0.295	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,648 associations by consensus.

NUDT16L1 vs TMEM186 — OV

Explore this scatter interactively →