NTSR1

Across TCGA patient cohorts, NTSR1 mutation is significantly associated with the RNA expression of many other genes, with 344 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTSR1-associated genes across cancer lineages are RNU6-1113P, ASB15-AS1, and TP53TG3GP. Each is linked with NTSR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NTSR1-to-partner and partner-to-NTSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1113P grouped by NTSR1-low versus NTSR1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTSR1→partner) and Y-score (partner→NTSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1113P →	+0.423	+7.632	<.001	<.001	3	3
LUAD	ASB15-AS1 →	+0.023	+3.415	.007	.009	3	3
GBM	TP53TG3GP →	+0.404	+5.189	<.001	.003	3	2
READ	LINC02335 →	+1.069	+5.219	<.001	.006	3	2
COAD	RNU6-41P →	+0.606	+4.721	<.001	.004	3	2
COAD	RNU6-298P →	+0.963	+4.120	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 344 associations by consensus.

RNU6-1113P by NTSR1 expression — BLCA

Explore this box plot interactively →