NT5C3A

Across TCGA patient cohorts, NT5C3A mutation is significantly associated with the RNA expression of many other genes, with 633 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5C3A-associated genes across cancer lineages are RFKP1, NCOA4P1, and LPP-AS2. Each is linked with NT5C3A in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C3A-to-partner and partner-to-NT5C3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFKP1 grouped by NT5C3A-low versus NT5C3A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C3A→partner) and Y-score (partner→NT5C3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RFKP1 →	+0.093	+2.434	.001	.009	3	2
UCEC	NCOA4P1 →	+0.085	+2.239	<.001	.001	3	2
UCEC	LPP-AS2 →	-0.393	-2.257	.008	.006	3	1
UCEC	SRXN1 →	+0.605	+3.343	<.001	.005	3	1
UCEC	ARF4P1 →	+0.570	+2.543	<.001	.009	3	1
UCEC	LINC01607 →	-0.769	-3.679	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 633 associations by consensus.

RFKP1 by NT5C3A expression — UCEC

Explore this box plot interactively →