NSUN6

Across TCGA patient cohorts, NSUN6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,621 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NSUN6-associated genes across cancer lineages are GTPBP4, MINDY3, and UPF2. Each is linked with NSUN6 in more than 3 cancer types. Because this analysis shows association rather than direction, both NSUN6-to-partner and partner-to-NSUN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSUN6 versus GTPBP4 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN6→partner) and Y-score (partner→NSUN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTPBP4 →	+0.575	+0.214	<.001	<.001	3	4
LSCC	MINDY3 →	+0.491	+0.400	.003	.001	3	4
UCEC	UPF2 →	+0.350	+0.240	.004	<.001	3	4
UCEC	RPP38 →	+0.491	+0.233	.001	<.001	3	4
LSCC	HSPA14 →	+0.767	+0.425	<.001	<.001	3	4
UCEC	PDSS1 →	+0.556	+0.347	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,621 associations by consensus.

NSUN6 vs GTPBP4 — HNSC

Explore this scatter interactively →