NSUN5

Across TCGA patient cohorts, NSUN5 protein abundance is significantly associated with the RNA expression of many other genes, with 17,370 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NSUN5-associated genes across cancer lineages are CDC20, DKC1, and TEDC2. Each is linked with NSUN5 in more than 7 cancer types. Because this analysis shows association rather than direction, both NSUN5-to-partner and partner-to-NSUN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSUN5 versus CDC20 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN5→partner) and Y-score (partner→NSUN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC20 →	+1.641	+0.297	<.001	<.001	3	8
HNSC	DKC1 →	+1.155	+0.338	<.001	<.001	3	8
UCEC	TEDC2 →	+1.061	+0.217	<.001	<.001	3	8
BRCA	CDT1 →	+1.231	+0.301	<.001	<.001	3	8
BRCA	MCM10 →	+1.121	+0.251	<.001	<.001	3	8
HNSC	AURKA →	+1.265	+0.300	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,370 associations by consensus.

NSUN5 vs CDC20 — BRCA

Explore this scatter interactively →