NSDHL

Across TCGA patient cohorts, NSDHL protein abundance is significantly associated with the RNA expression of many other genes, with 11,627 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NSDHL-associated genes across cancer lineages are PPP1R16B, BCAP31, and MMRN1. Each is linked with NSDHL in more than 7 cancer types. Because this analysis shows association rather than direction, both NSDHL-to-partner and partner-to-NSDHL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSDHL versus PPP1R16B in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSDHL→partner) and Y-score (partner→NSDHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	-1.346	-0.251	<.001	<.001	3	8
HNSC	BCAP31 →	+0.789	+0.217	.003	.002	3	7
COAD	MMRN1 →	-1.248	-0.234	<.001	.004	3	7
HNSC	ITM2A →	-1.204	-0.379	<.001	<.001	3	7
GBM	C7 →	-1.705	-0.258	<.001	.001	3	7
HNSC	SLC10A3 →	+0.580	+0.254	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,627 associations by consensus.

NSDHL vs PPP1R16B — GBM

Explore this scatter interactively →