NSDHL

Across TCGA cell cohorts, NSDHL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,127 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NSDHL-associated GO terms across cancer lineages are Secondary alcohol biosynthetic process, Cholesterol biosynthetic process via desmosterol, and Zymosterol metabolic process. Each is linked with NSDHL in more than 18 cancer types. Because this analysis shows association rather than direction, both NSDHL-to-partner and partner-to-NSDHL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Secondary alcohol biosynthetic process grouped by NSDHL-low versus NSDHL-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSDHL→partner) and Y-score (partner→NSDHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Secondary alcohol biosynthetic process →	+0.217	+1.052	<.001	<.001	3	19
BONE	Cholesterol biosynthetic process via desmosterol →	+0.230	+1.006	<.001	<.001	3	19
BONE	Zymosterol metabolic process →	+0.244	+1.006	<.001	<.001	3	19
BONE	Zymosterol biosynthetic process →	+0.244	+1.006	<.001	<.001	3	19
BONE	Cholesterol biosynthetic process →	+0.217	+1.052	<.001	<.001	3	19
BONE	Farnesyl diphosphate biosynthetic process, mevalonate pathway →	+0.216	+1.003	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,127 associations by consensus.

Secondary alcohol biosynthetic process by NSDHL expression — BONE

Explore this box plot interactively →